Incremental Cost per Responder (PASI-75, PASI-90 and PASI-100) Based on a Network Meta-Analysis of Biologic Therapies for Psoriasis: Spain 2018
نویسندگان
چکیده
منابع مشابه
Effect of Biologic Agents on Non-PASI Outcomes in Moderate-to-Severe Plaque Psoriasis: Systematic Review and Meta-Analyses
INTRODUCTION The objective of this review was to conduct a systematic review with meta-analysis and Bayesian mixed treatment comparisons (MTC) evaluating the impact of biologics on non-Psoriasis Area and Severity Index (PASI) health outcomes in patients with moderate-to-severe plaque psoriasis. METHODS MEDLINE and Cochrane Central Register of Controlled Trials were searched from 1966 to May 2...
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Psoriasis is a chronic, immune-mediated inflammatory disorder affecting 2--3% of general population, being both physically and emotionally debilitating. Due to the rapid advances in the understanding of psoriasis pathogenesis, several targeted medications, aiming specific components of the immune system, have been and are currently being developed. These biologic therapies are a major technolog...
متن کاملEfficacy and Cost-Efficacy of Biologic Therapies for Moderate to Severe Psoriasis: A Meta-Analysis and Cost-Efficacy Analysis Using the Intention-to-Treat Principle
BACKGROUND Compared to conventional therapies, biologics are more effective but expensive in treating psoriasis. OBJECTIVE To evaluate the efficacy and cost-efficacy of biologic therapies for psoriasis. METHODS We conducted a meta-analysis to calculate the efficacy of etanercept, adalimumab, infliximab, and ustekinumab for at least 75% reduction in the Psoriasis Area and Severity Index scor...
متن کاملCost per responder associated with biologic therapies for Crohn's disease, psoriasis, and rheumatoid arthritis.
INTRODUCTION Biologic therapies have demonstrated efficacy and safety in several chronic systemic disorders. The authors indirectly compared response rates and costs per responder associated with biologic treatments for moderate-to-severe Crohn's disease (CD), psoriasis (Ps), and/or rheumatoid arthritis (RA). METHODS A systematic literature search was performed to identify phase 3 randomized ...
متن کاملObjective Assessment of Psoriasis Lesion Thickness for PASI Scoring using 3D Digital Imaging
Psoriasis is a chronic inflammatory skin condition which affects 2-3% of population around the world. Psoriasis Area and Severity Index (PASI) is a gold standard to assess psoriasis severity as well as the treatment efficacy. Although a gold standard, PASI is rarely used because it is tedious and complex. In practice, PASI score is determined subjectively by dermatologists, therefore inter and ...
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ژورنال
عنوان ژورنال: Actas Dermo-Sifiliográficas (English Edition)
سال: 2019
ISSN: 1578-2190
DOI: 10.1016/j.adengl.2018.12.012